General Information
SPKB ID SPKB06250
Signal sequence MSVSFLIFLPVLGLPWGVLS
Length 20
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06250.cif
Physicochemical Information
Molecular weight 2175.70024
Aliphatic index 160.5
Isoelectric point 6.099999998
Charge (pH=7) -0.002015701
Topological polar surface area 675.12
Aromaticity 0.15
Average rotatable bonds 3.2
Number of hydrogen bond donors 23
Number of hydrogen bond acceptors 25
X logP energy 0.0687
Hydropathy 
Literature Information
Title Essentially Leading Antibody Production: An Investigation of Amino Acids, Myeloma, and Natural V-Region Signal Peptides in Producing Pertuzumab and Trastuzumab Variants
DOI 10.3389/fimmu.2020.604318,
Publication Year 2020
PubMed ID 33365032,
Patent ID NA,
