General Information
SPKB ID SPKB06249
Signal sequence MGSTAILALLLAVLQGVCS
Length 19
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06249.cif
Physicochemical Information
Molecular weight 1860.30064
Aliphatic index 169.4736842
Isoelectric point 5.922539791
Charge (pH=7) -0.063990417
Topological polar surface area 690.9
Aromaticity 0
Average rotatable bonds 3.210526316
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 26
X logP energy -5.6504
Hydropathy 
Literature Information
Title Essentially Leading Antibody Production: An Investigation of Amino Acids, Myeloma, and Natural V-Region Signal Peptides in Producing Pertuzumab and Trastuzumab Variants
DOI 10.3389/fimmu.2020.604318,
Publication Year 2020
PubMed ID 33365032,
Patent ID NA,
