General Information
SPKB ID SPKB06248
Signal sequence MEFGLSWVFLVAILKGVQC
Length 19
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06248.cif
Physicochemical Information
Molecular weight 2140.62954
Aliphatic index 133.1578947
Isoelectric point 6.231833229
Charge (pH=7) -0.062510328
Topological polar surface area 729.55
Aromaticity 0.157894737
Average rotatable bonds 3.631578947
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 26
X logP energy -1.2963
Hydropathy 
Literature Information
Title Essentially Leading Antibody Production: An Investigation of Amino Acids, Myeloma, and Natural V-Region Signal Peptides in Producing Pertuzumab and Trastuzumab Variants
DOI 10.3389/fimmu.2020.604318,
Publication Year 2020
PubMed ID 33365032,
Patent ID NA,
