General Information
SPKB ID SPKB06247
Signal sequence MLPSQLIGFLLLWVPASRG
Length 19
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06247.cif
Physicochemical Information
Molecular weight 2098.57724
Aliphatic index 143.6842105
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 730.78
Aromaticity 0.105263158
Average rotatable bonds 3.368421053
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 25
X logP energy -2.41443
Hydropathy 
Literature Information
Title Essentially Leading Antibody Production: An Investigation of Amino Acids, Myeloma, and Natural V-Region Signal Peptides in Producing Pertuzumab and Trastuzumab Variants
DOI 10.3389/fimmu.2020.604318,
Publication Year 2020
PubMed ID 33365032,
Patent ID NA,
