General Information
SPKB ID SPKB06246
Signal sequence MGSQVHLLSFLLLWISDTRA
Length 20
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06246.cif
Physicochemical Information
Molecular weight 2287.70494
Aliphatic index 136.5
Isoelectric point 7.550936504
Charge (pH=7) 0.089336563
Topological polar surface area 883.9
Aromaticity 0.1
Average rotatable bonds 3.7
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 30
X logP energy -5.75983
Hydropathy 
Literature Information
Title Essentially Leading Antibody Production: An Investigation of Amino Acids, Myeloma, and Natural V-Region Signal Peptides in Producing Pertuzumab and Trastuzumab Variants
DOI 10.3389/fimmu.2020.604318,
Publication Year 2020
PubMed ID 33365032,
Patent ID NA,
