General Information
SPKB ID SPKB06245
Signal sequence MRLPAQLLGLLMLWVPGSSA
Length 20
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06245.cif
Physicochemical Information
Molecular weight 2153.67204
Aliphatic index 141.5
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 759.88
Aromaticity 0.05
Average rotatable bonds 3.35
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 27
X logP energy -3.39933
Hydropathy 
Literature Information
Title Essentially Leading Antibody Production: An Investigation of Amino Acids, Myeloma, and Natural V-Region Signal Peptides in Producing Pertuzumab and Trastuzumab Variants
DOI 10.3389/fimmu.2020.604318,
Publication Year 2020
PubMed ID 33365032,
Patent ID NA,
