General Information
SPKB ID SPKB06243
Signal sequence MGPGARGRRRRRRPMSPPPPPPPVRALPLLLLLAGPGAA
Length 39
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..39
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06243.cif
Physicochemical Information
Molecular weight 4104.00484
Aliphatic index 80.25641026
Isoelectric point 13.34510696
Charge (pH=7) 7.997957809
Topological polar surface area 1587.86
Aromaticity 0
Average rotatable bonds 3.025641026
Number of hydrogen bond donors 54
Number of hydrogen bond acceptors 51
X logP energy -14.81734
Hydropathy
Literature Information
Title The translation attenuating arginine-rich sequence in the extended signal peptide of the protein-tyrosine phosphatase PTPRJ/DEP1 is conserved in mammals
DOI 10.1371/journal.pone.0240498,
Publication Year 2020
PubMed ID 33296397,
Patent ID NA,