General Information
SPKB ID SPKB06242
Signal sequence MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARA
Length 55
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..55
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8XFP,
Predicted Structure ID SPKB06242.cif
Physicochemical Information
Molecular weight 5927.14844
Aliphatic index 83.63636364
Isoelectric point 13.31292206
Charge (pH=7) 14.93595991
Topological polar surface area 2536.01
Aromaticity 0
Average rotatable bonds 3.381818182
Number of hydrogen bond donors 95
Number of hydrogen bond acceptors 76
X logP energy -28.71165
Hydropathy 
Literature Information
Title The translation attenuating arginine-rich sequence in the extended signal peptide of the protein-tyrosine phosphatase PTPRJ/DEP1 is conserved in mammals
DOI 10.1371/journal.pone.0240498,
Publication Year 2020
PubMed ID 33296397,
Patent ID NA,
