General Information
SPKB ID SPKB06238
Signal sequence QMRPVSRVL
Length 9
Organism Homo sapiens (Human)
UniProt ID NA,
Motif 1..9
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06238.cif
Physicochemical Information
Molecular weight 1085.33304
Aliphatic index 107.7777778
Isoelectric point 12.50010931
Charge (pH=7) 1.997977677
Topological polar surface area 474.45
Aromaticity 0
Average rotatable bonds 3.888888889
Number of hydrogen bond donors 17
Number of hydrogen bond acceptors 15
X logP energy -4.32156
Hydropathy
Literature Information
Title A signal peptide derived from Hsp60 induces protective cytotoxic T lymphocyte immunity against lymphoid malignancies independently of TAP and classical MHC-I
DOI 10.1016/j.canlet.2020.08.016,
Publication Year 2020
PubMed ID 32829008,
Patent ID NA,