SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06235

Signal sequence   MANNCNLVSVLCVILVLTLFHNPITVAG

Length  28

Organism  Arabidopsis thaliana (Mouse-ear cress)

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06235.cif

Structure  SPKB06235.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2969.61174

Aliphatic index  156.4285714

Isoelectric point  7.253156577

Charge (pH=7)   -0.035056042

Topological polar surface area  1101.96

Aromaticity  0.035714286

Average rotatable bonds  3.321428571

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  40

X logP energy  -8.6553

Hydropathy 



Literature Information


Title  Yeast-based reporter assay system for identifying the requirements of intramembrane proteolysis by signal peptide peptidase of Arabidopsis thaliana

DOI  10.1002/2211-5463.12936,

Publication Year  2020

PubMed ID  32686366,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.