SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06229

Signal sequence   AMISYSTIVVALLASFMICSVSA

Length  23

Organism  Arabidopsis thaliana (Mouse-ear cress)

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06229.cif

Structure  SPKB06229.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2377.89794

Aliphatic index  140

Isoelectric point  5.919503212

Charge (pH=7)   -0.064840831

Topological polar surface area  845.13

Aromaticity  0.086956522

Average rotatable bonds  3.260869565

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  34

X logP energy  -6.6887

Hydropathy 



Literature Information


Title  Yeast-based reporter assay system for identifying the requirements of intramembrane proteolysis by signal peptide peptidase of Arabidopsis thaliana

DOI  10.1002/2211-5463.12936,

Publication Year  2020

PubMed ID  32686366,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.