SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06224

Signal sequence   AVIVWWLLTVVVVAFHSASA

Length  20

Organism  Arabidopsis thaliana (Mouse-ear cress)

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06224.cif

Structure  SPKB06224.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2168.60984

Aliphatic index  165.5

Isoelectric point  7.550323994

Charge (pH=7)   0.08889339

Topological polar surface area  737.17

Aromaticity  0.15

Average rotatable bonds  3.1

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  25

X logP energy  -1.2147

Hydropathy 



Literature Information


Title  Yeast-based reporter assay system for identifying the requirements of intramembrane proteolysis by signal peptide peptidase of Arabidopsis thaliana

DOI  10.1002/2211-5463.12936,

Publication Year  2020

PubMed ID  32686366,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.