SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06221

Signal sequence   EGVTVVSFFLLFIATAMA

Length  18

Organism  Arabidopsis thaliana (Mouse-ear cress)

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06221.cif

Structure  SPKB06221.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1916.30584

Aliphatic index  130

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  656.01

Aromaticity  0.166666667

Average rotatable bonds  3.277777778

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  24

X logP energy  -2.4628

Hydropathy 



Literature Information


Title  Yeast-based reporter assay system for identifying the requirements of intramembrane proteolysis by signal peptide peptidase of Arabidopsis thaliana

DOI  10.1002/2211-5463.12936,

Publication Year  2020

PubMed ID  32686366,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.