SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06213

Signal sequence   MKNMSCKGVVSVTLFFSFLTINTLIHI

Length  27

Organism  Bacillus subtilis DB104

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06213.cif

Structure  SPKB06213.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3044.72194

Aliphatic index  118.888888888889

Isoelectric point  9.67734675388783

Charge (pH=7)   2.02632860667247

Topological polar surface area  1108.2

Aromaticity  0.111111111111111

Average rotatable bonds  3.74074074074074

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  42

X logP energy  -7.86289999999997

Hydropathy 



Literature Information


Title  Signal Peptide Efficiency: From High-Throughput Data to Prediction and Explanation

DOI  10.1021/acssynbio.2c00328,

Publication Year  2023

PubMed ID  36649479,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.