SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06212

Signal sequence   MNKPTKLFSTLALAAKRKRFFAGTIHA

Length  27

Organism  Bacillus subtilis DB104

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06212.cif

Structure  SPKB06212.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3019.64764

Aliphatic index  76.2962962962963

Isoelectric point  12.5595904951915

Charge (pH=7)   6.08770663229332

Topological polar surface area  1191.7

Aromaticity  0.111111111111111

Average rotatable bonds  3.74074074074074

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  41

X logP energy  -10.0757600000001

Hydropathy 



Literature Information


Title  Signal Peptide Efficiency: From High-Throughput Data to Prediction and Explanation

DOI  10.1021/acssynbio.2c00328,

Publication Year  2023

PubMed ID  36649479,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.