SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06209

Signal sequence   MKRLLSTLLIGIMLLTFRRSHFA

Length  23

Organism  Bacillus subtilis DB104

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06209.cif

Structure  SPKB06209.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2718.40384

Aliphatic index  140

Isoelectric point  12.8074281075969

Charge (pH=7)   4.08858842254908

Topological polar surface area  1024.84

Aromaticity  0.0869565217391304

Average rotatable bonds  4.04347826086957

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  35

X logP energy  -5.2935899999999

Hydropathy 



Literature Information


Title  Signal Peptide Efficiency: From High-Throughput Data to Prediction and Explanation

DOI  10.1021/acssynbio.2c00328,

Publication Year  2023

PubMed ID  36649479,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.