SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06203

Signal sequence   MPDDDVDEDEVFFLDEDEFSAVTATASA

Length  28

Organism  Bacillus subtilis DB104

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06203.cif

Structure  SPKB06203.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3081.17554

Aliphatic index  59.2857142857143

Isoelectric point  2.88115099468268

Charge (pH=7)   -10.991789820539

Topological polar surface area  1331.45

Aromaticity  0.107142857142857

Average rotatable bonds  3.5

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  45

X logP energy  -13.9027

Hydropathy 



Literature Information


Title  Signal Peptide Efficiency: From High-Throughput Data to Prediction and Explanation

DOI  10.1021/acssynbio.2c00328,

Publication Year  2023

PubMed ID  36649479,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.