SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06202

Signal sequence   MGLGKKLSVAVAASFMSLSISLSKRVKR

Length  28

Organism  Bacillus subtilis DB104

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06202.cif

Structure  SPKB06202.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2965.65264

Aliphatic index  111.428571428571

Isoelectric point  12.5595898171887

Charge (pH=7)   5.99679754138423

Topological polar surface area  1198.28

Aromaticity  0.0357142857142857

Average rotatable bonds  3.78571428571429

Number of hydrogen bond donors  45

Number of hydrogen bond acceptors  43

X logP energy  -12.24586

Hydropathy 



Literature Information


Title  Signal Peptide Efficiency: From High-Throughput Data to Prediction and Explanation

DOI  10.1021/acssynbio.2c00328,

Publication Year  2023

PubMed ID  36649479,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.