SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06198

Signal sequence   MRKFRLVSLSLVALIHATATSQNVALA

Length  27

Organism  Bacillus subtilis DB104

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06198.cif

Structure  SPKB06198.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2911.50214

Aliphatic index  137.407407407407

Isoelectric point  12.5164789548144

Charge (pH=7)   3.08859173384933

Topological polar surface area  1185.75

Aromaticity  0.037037037037037

Average rotatable bonds  3.59259259259259

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  40

X logP energy  -11.15626

Hydropathy 



Literature Information


Title  Signal Peptide Efficiency: From High-Throughput Data to Prediction and Explanation

DOI  10.1021/acssynbio.2c00328,

Publication Year  2023

PubMed ID  36649479,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.