SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06196

Signal sequence   MLKRTSFVSSLFISSAVLLLTSTQGHI

Length  27

Organism  Bacillus subtilis DB104

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06196.cif

Structure  SPKB06196.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2937.49064

Aliphatic index  126.296296296296

Isoelectric point  11.6517897220329

Charge (pH=7)   2.08859504514958

Topological polar surface area  1161.68

Aromaticity  0.0740740740740741

Average rotatable bonds  3.62962962962963

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  42

X logP energy  -11.75263

Hydropathy 



Literature Information


Title  Signal Peptide Efficiency: From High-Throughput Data to Prediction and Explanation

DOI  10.1021/acssynbio.2c00328,

Publication Year  2023

PubMed ID  36649479,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.