SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06195

Signal sequence   MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPN

Length  36

Organism  Escherichia coli

UniProt ID  NA,

Motif  1..36



Activity Information


Pathway  Tat

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Tat/SPI



Structure Information


PDB ID  7LB8,

Predicted Structure ID  SPKB06195.cif

Structure  SPKB06195.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3931.69094

Aliphatic index  114.1666667

Isoelectric point  12.19913522

Charge (pH=7)   2.089329941

Topological polar surface area  1553.34

Aromaticity  0.027777778

Average rotatable bonds  3.472222222

Number of hydrogen bond donors  54

Number of hydrogen bond acceptors  53

X logP energy  -13.98099

Hydropathy 



Literature Information


Title  N-Terminal Fused Signal Peptide Prompted Extracellular Production of a Bacillus-Derived Alkaline and Thermo Stable Xylanase in E. coli Through Cell Autolysis

DOI  10.1007/s12010-020-03323-9,

Publication Year  2020

PubMed ID  32382941,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.