SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06189

Signal sequence   MTRSKPVNRTAFCCLSLTTALILTAC

Length  26

Organism  Neisseria meningitidis

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06189.cif

Structure  SPKB06189.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2815.41834

Aliphatic index  97.69230769

Isoelectric point  8.99394969

Charge (pH=7)   2.811758495

Topological polar surface area  1116.55

Aromaticity  0.038461538

Average rotatable bonds  3.461538462

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  42

X logP energy  -12.82456

Hydropathy 



Literature Information


Title  Variant Signal Peptides of Vaccine Antigen, FHbp, Impair Processing Affecting Surface Localization and Antibody-Mediated Killing in Most Meningococcal Isolates

DOI  10.3389/fmicb.2019.02847,

Publication Year  2019

PubMed ID  31921030,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.