SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06179

Signal sequence   MAKTNSYKKVIAGTMTAAMVAGVVSPVAA

Length  29

Organism  Bacillus thuringiensis

UniProt ID  Q9ZES5,

Motif  1..29



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  9G93,

Predicted Structure ID  SPKB06179.cif

Structure  SPKB06179.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2868.46134

Aliphatic index  87.5862069

Isoelectric point  10.64292272

Charge (pH=7)   2.996248784

Topological polar surface area  1111.86

Aromaticity  0.034482759

Average rotatable bonds  3.206896552

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  43

X logP energy  -12.1959

Hydropathy 



Literature Information


Title  Analysis of different signal peptides for the secretory production of Ama r 2 in gram-positive systems (Lactococcus lactis)

DOI  10.1016/j.micpath.2019.103819,

Publication Year  2020

PubMed ID  31669829,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.