General Information
SPKB ID SPKB06178
Signal sequence MNKKKLGIRLLSLLALGGFVLANPVFA
Length 27
Organism Streptococcus pyogenes serotype M28
UniProt ID NA,
Motif 1..27
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Extracellular environment
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06178.cif
Physicochemical Information
Molecular weight 2884.60584
Aliphatic index 148.1481481
Isoelectric point 11.92450937
Charge (pH=7) 3.997095887
Topological polar surface area 1057.5
Aromaticity 0.074074074
Average rotatable bonds 3.62962963
Number of hydrogen bond donors 36
Number of hydrogen bond acceptors 36
X logP energy -5.22413
Hydropathy 
Literature Information
Title Analysis of different signal peptides for the secretory production of Ama r 2 in gram-positive systems (Lactococcus lactis)
DOI 10.1016/j.micpath.2019.103819,
Publication Year 2020
PubMed ID 31669829,
Patent ID NA,
