SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06175

Signal sequence   MKTKQNIARKLSRVVLLSTLVLSSAAPISAAFA

Length  33

Organism  Streptococcus intermedius

UniProt ID  NA,

Motif  1..33



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06175.cif

Structure  SPKB06175.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3486.22054

Aliphatic index  127.2727273

Isoelectric point  12.54607567

Charge (pH=7)   4.997092575

Topological polar surface area  1415.38

Aromaticity  0.03030303

Average rotatable bonds  3.575757576

Number of hydrogen bond donors  51

Number of hydrogen bond acceptors  49

X logP energy  -14.39846

Hydropathy 



Literature Information


Title  Analysis of different signal peptides for the secretory production of Ama r 2 in gram-positive systems (Lactococcus lactis)

DOI  10.1016/j.micpath.2019.103819,

Publication Year  2020

PubMed ID  31669829,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.