SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06174

Signal sequence   MKNKVLKTLVLFLFAVLGIFAMQTVEA

Length  27

Organism  Streptococcus equisimilis

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06174.cif

Structure  SPKB06174.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3025.78784

Aliphatic index  140.7407407

Isoelectric point  10.506919

Charge (pH=7)   1.998874321

Topological polar surface area  1061.92

Aromaticity  0.111111111

Average rotatable bonds  3.814814815

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  38

X logP energy  -3.0166

Hydropathy 



Literature Information


Title  Analysis of different signal peptides for the secretory production of Ama r 2 in gram-positive systems (Lactococcus lactis)

DOI  10.1016/j.micpath.2019.103819,

Publication Year  2020

PubMed ID  31669829,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.