SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06173

Signal sequence   MKNYLSFGMFALLFALTFGTVNSVQA

Length  26

Organism  Streptococcus equisimilis

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06173.cif

Structure  SPKB06173.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2871.40484

Aliphatic index  93.84615385

Isoelectric point  9.298300651

Charge (pH=7)   0.996838851

Topological polar surface area  1047.26

Aromaticity  0.192307692

Average rotatable bonds  3.538461538

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  38

X logP energy  -7.346

Hydropathy 



Literature Information


Title  Analysis of different signal peptides for the secretory production of Ama r 2 in gram-positive systems (Lactococcus lactis)

DOI  10.1016/j.micpath.2019.103819,

Publication Year  2020

PubMed ID  31669829,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.