SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06171

Signal sequence   MNNRMLSFPSMLFLLAFGIVLSVSAGTTHA

Length  30

Organism  Streptococcus downei

UniProt ID  P39653,

Motif  1..30



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06171.cif

Structure  SPKB06171.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3226.86054

Aliphatic index  107.3333333

Isoelectric point  10.5517587

Charge (pH=7)   1.088890079

Topological polar surface area  1196.57

Aromaticity  0.1

Average rotatable bonds  3.433333333

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  44

X logP energy  -10.42713

Hydropathy 



Literature Information


Title  Analysis of different signal peptides for the secretory production of Ama r 2 in gram-positive systems (Lactococcus lactis)

DOI  10.1016/j.micpath.2019.103819,

Publication Year  2020

PubMed ID  31669829,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.