SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06165

Signal sequence   MKKHGFRFWLLAIVGLLGMVLSLSQPPKQVAA

Length  32

Organism  Lactobacillus casei

UniProt ID  NA,

Motif  1..32



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06165.cif

Structure  SPKB06165.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3537.37464

Aliphatic index  121.875

Isoelectric point  11.9245139

Charge (pH=7)   4.088004977

Topological polar surface area  1258.91

Aromaticity  0.09375

Average rotatable bonds  3.625

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  44

X logP energy  -5.46863

Hydropathy 



Literature Information


Title  Analysis of different signal peptides for the secretory production of Ama r 2 in gram-positive systems (Lactococcus lactis)

DOI  10.1016/j.micpath.2019.103819,

Publication Year  2020

PubMed ID  31669829,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.