SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06160

Signal sequence   MKFNKKRVAIATFIALIFVSFFTISSIQDNQTNA

Length  34

Organism  Lactococcus lactis

UniProt ID  NA,

Motif  1..34



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06160.cif

Structure  SPKB06160.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3865.54874

Aliphatic index  97.64705882

Isoelectric point  11.07952224

Charge (pH=7)   2.997542371

Topological polar surface area  1537.71

Aromaticity  0.147058824

Average rotatable bonds  3.823529412

Number of hydrogen bond donors  53

Number of hydrogen bond acceptors  52

X logP energy  -13.56703

Hydropathy 



Literature Information


Title  Analysis of different signal peptides for the secretory production of Ama r 2 in gram-positive systems (Lactococcus lactis)

DOI  10.1016/j.micpath.2019.103819,

Publication Year  2020

PubMed ID  31669829,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.