SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06152

Signal sequence   MKLWMRKTLVVLFTIVTFGLVSPPAALMA

Length  29

Organism  Bacillus subtilis

UniProt ID  NA,

Motif  1..29



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06152.cif

Structure  SPKB06152.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3235.09714

Aliphatic index  131.0344828

Isoelectric point  11.82305527

Charge (pH=7)   2.99739092

Topological polar surface area  1071.19

Aromaticity  0.103448276

Average rotatable bonds  3.517241379

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  40

X logP energy  -2.29853

Hydropathy 



Literature Information


Title  Engineering a highly efficient expression system to produce BcaPRO protease in Bacillus subtilis by an optimized promoter and signal peptide

DOI  10.1016/j.ijbiomac.2019.07.175,

Publication Year  2019

PubMed ID  31356949,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.