SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06143

Signal sequence   MKKFPKKLLPIASSSIAFSSLASGSVPEASA

Length  31

Organism  Bacillus subtilis

UniProt ID  NA,

Motif  1..31



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06143.cif

Structure  SPKB06143.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3150.72414

Aliphatic index  88.38709677

Isoelectric point  10.80270634

Charge (pH=7)   2.998579287

Topological polar surface area  1213.17

Aromaticity  0.064516129

Average rotatable bonds  3.322580645

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  46

X logP energy  -13.364

Hydropathy 



Literature Information


Title  Factors Influencing Recombinant Protein Secretion Efficiency in Gram-Positive Bacteria: Signal Peptide and Beyond

DOI  10.3389/fbioe.2019.00139,

Publication Year  2019

PubMed ID  31245367,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.