SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06142

Signal sequence   MRSKKLWISLLFALTLIFTMAFSNMSA

Length  27

Organism  Bacillus licheniformis WX-02

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06142.cif

Structure  SPKB06142.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3121.85074

Aliphatic index  112.2222222

Isoelectric point  11.82305527

Charge (pH=7)   2.99739092

Topological polar surface area  1114.12

Aromaticity  0.148148148

Average rotatable bonds  3.851851852

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  41

X logP energy  -5.77563

Hydropathy 



Literature Information


Title  Factors Influencing Recombinant Protein Secretion Efficiency in Gram-Positive Bacteria: Signal Peptide and Beyond

DOI  10.3389/fbioe.2019.00139,

Publication Year  2019

PubMed ID  31245367,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.