SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06137

Signal sequence   KNMSCKLVVSVTLFFSFLTIGPLAHA

Length  26

Organism  Artificial

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Increase pullulanase activity by 1.08 times

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06137.cif

Structure  SPKB06137.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2824.43534

Aliphatic index  116.153846153846

Isoelectric point  9.67734675388783

Charge (pH=7)   2.02632860667247

Topological polar surface area  1006.99

Aromaticity  0.115384615384615

Average rotatable bonds  3.46153846153846

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  38

X logP energy  -6.85709999999992

Hydropathy 



Literature Information


Title  Signal peptide for promoting extracellular expression of pullulanase

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  CN111826377B,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.