General Information
SPKB ID SPKB06136
Signal sequence MKKRGAFLGLLLVSACASVFA
Length 21
Organism Escherichia coli
UniProt ID NA,
Motif 1..21
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Periplasmic space
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06136.cif
Physicochemical Information
Molecular weight 2182.71374
Aliphatic index 120.952381
Isoelectric point 10.79319833
Charge (pH=7) 2.935416204
Topological polar surface area 799.72
Aromaticity 0.095238095
Average rotatable bonds 3.476190476
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 29
X logP energy -5.39273
Hydropathy 
Literature Information
Title In silico analysis of different signal peptides for the secretory production of recombinant human keratinocyte growth factor in Escherichia coli
DOI 10.1016/j.compbiolchem.2019.03.003,
Publication Year 2019
PubMed ID 30999249,
Patent ID NA,
