General Information
SPKB ID SPKB06133
Signal sequence MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATA
Length 39
Organism Escherichia coli
UniProt ID P33225,
Motif 1..39
Activity Information
Pathway Tat
Natural/Artificial Artificial
Subcellular location Periplasmic space
Secretion efficiency NA
Type Tat/SPI
Structure Information
PDB ID 9H4T,
Predicted Structure ID SPKB06133.cif
Physicochemical Information
Molecular weight 4215.90764
Aliphatic index 90.25641026
Isoelectric point 12.67612163
Charge (pH=7) 3.998414227
Topological polar surface area 1814.94
Aromaticity 0.051282051
Average rotatable bonds 3.564102564
Number of hydrogen bond donors 64
Number of hydrogen bond acceptors 58
X logP energy -21.49625
Hydropathy 
Literature Information
Title In silico analysis of different signal peptides for the secretory production of recombinant human keratinocyte growth factor in Escherichia coli
DOI 10.1016/j.compbiolchem.2019.03.003,
Publication Year 2019
PubMed ID 30999249,
Patent ID NA,
