General Information
SPKB ID SPKB06132
Signal sequence MKQALRVAFGFLILWASVLHA
Length 21
Organism Escherichia coli
UniProt ID NA,
Motif 1..21
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Periplasmic space
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 1C5K,
Predicted Structure ID SPKB06132.cif
Physicochemical Information
Molecular weight 2371.91514
Aliphatic index 139.5238095
Isoelectric point 11.65178972
Charge (pH=7) 2.088595045
Topological polar surface area 841.03
Aromaticity 0.142857143
Average rotatable bonds 3.619047619
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 28
X logP energy -2.07383
Hydropathy 
Literature Information
Title In silico analysis of different signal peptides for the secretory production of recombinant human keratinocyte growth factor in Escherichia coli
DOI 10.1016/j.compbiolchem.2019.03.003,
Publication Year 2019
PubMed ID 30999249,
Patent ID NA,
