General Information
SPKB ID SPKB06129
Signal sequence MKKWLLAAGLGLALATSAQA
Length 20
Organism Escherichia coli
UniProt ID NA,
Motif 1..20
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Periplasmic space
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06129.cif
Physicochemical Information
Molecular weight 2014.45684
Aliphatic index 127.5
Isoelectric point 10.80537956
Charge (pH=7) 1.997394232
Topological polar surface area 767.6
Aromaticity 0.05
Average rotatable bonds 3.35
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 27
X logP energy -5.4041
Hydropathy 
Literature Information
Title In silico analysis of different signal peptides for the secretory production of recombinant human keratinocyte growth factor in Escherichia coli
DOI 10.1016/j.compbiolchem.2019.03.003,
Publication Year 2019
PubMed ID 30999249,
Patent ID NA,
