General Information
SPKB ID SPKB06126
Signal sequence MTMTRLKISKTLLAVMLTSAVATGSAYA
Length 28
Organism Escherichia coli
UniProt ID NA,
Motif 1..28
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Periplasmic space
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06126.cif
Physicochemical Information
Molecular weight 2930.57294
Aliphatic index 108.2142857
Isoelectric point 10.90180955
Charge (pH=7) 2.996540506
Topological polar surface area 1145.03
Aromaticity 0.035714286
Average rotatable bonds 3.5
Number of hydrogen bond donors 43
Number of hydrogen bond acceptors 44
X logP energy -11.62893
Hydropathy 
Literature Information
Title In silico analysis of different signal peptides for the secretory production of recombinant human keratinocyte growth factor in Escherichia coli
DOI 10.1016/j.compbiolchem.2019.03.003,
Publication Year 2019
PubMed ID 30999249,
Patent ID NA,
