General Information
SPKB ID SPKB06121
Signal sequence MKSLFKVTLLATTMAVALHAPITFA
Length 25
Organism Escherichia coli
UniProt ID NA,
Motif 1..25
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Periplasmic space
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06121.cif
Physicochemical Information
Molecular weight 2676.31444
Aliphatic index 121.2
Isoelectric point 10.80542203
Charge (pH=7) 2.088303323
Topological polar surface area 934.8
Aromaticity 0.08
Average rotatable bonds 3.4
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 36
X logP energy -5.0874
Hydropathy 
Literature Information
Title In silico analysis of different signal peptides for the secretory production of recombinant human keratinocyte growth factor in Escherichia coli
DOI 10.1016/j.compbiolchem.2019.03.003,
Publication Year 2019
PubMed ID 30999249,
Patent ID NA,
