SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06119

Signal sequence   MILNRLSTLGIITFGPMLSFAPGPPPGPPRVS

Length  32

Organism  Yersinia pestis

UniProt ID  NA,

Motif  1..32



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06119.cif

Structure  SPKB06119.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3335.02894

Aliphatic index  97.5

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  1171.93

Aromaticity  0.0625

Average rotatable bonds  3

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  43

X logP energy  -9.37326

Hydropathy 



Literature Information


Title  In silico analysis of different signal peptides for the secretory production of recombinant human keratinocyte growth factor in Escherichia coli

DOI  10.1016/j.compbiolchem.2019.03.003,

Publication Year  2019

PubMed ID  30999249,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.