General Information
SPKB ID SPKB06118
Signal sequence MEFFKKTALAALVMGFSGAALA
Length 22
Organism Escherichia coli
UniProt ID P00805,
Motif 1..22
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Periplasmic space
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06118.cif
Physicochemical Information
Molecular weight 2274.76464
Aliphatic index 93.63636364
Isoelectric point 9.537300927
Charge (pH=7) 0.999169354
Topological polar surface area 804.22
Aromaticity 0.136363636
Average rotatable bonds 3.409090909
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 30
X logP energy -4.5142
Hydropathy 
Literature Information
Title In silico analysis of different signal peptides for the secretory production of recombinant human keratinocyte growth factor in Escherichia coli
DOI 10.1016/j.compbiolchem.2019.03.003,
Publication Year 2019
PubMed ID 30999249,
Patent ID NA,
