General Information
SPKB ID SPKB06117
Signal sequence MHKWILTWILPTLLYRSCFHIICLVGTISLA
Length 31
Organism Escherichia coli
UniProt ID NA,
Motif 1..31
Activity Information
Pathway Sec
Natural/Artificial Artificial
Subcellular location Periplasmic space
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06117.cif
Physicochemical Information
Molecular weight 3643.51334
Aliphatic index 150.9677419
Isoelectric point 8.803918743
Charge (pH=7) 2.05470429
Topological polar surface area 1225.77
Aromaticity 0.129032258
Average rotatable bonds 3.64516129
Number of hydrogen bond donors 47
Number of hydrogen bond acceptors 45
X logP energy -2.03453
Hydropathy 
Literature Information
Title In silico analysis of different signal peptides for the secretory production of recombinant human keratinocyte growth factor in Escherichia coli
DOI 10.1016/j.compbiolchem.2019.03.003,
Publication Year 2019
PubMed ID 30999249,
Patent ID NA,
