SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06114

Signal sequence   MRSYIKSILVCVILLILFVPTALA

Length  24

Organism  Bacillus subtilis DB104

UniProt ID  NA,

Motif  1..24



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06114.cif

Structure  SPKB06114.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2677.42904

Aliphatic index  190.833333333333

Isoelectric point  9.44786983635277

Charge (pH=7)   1.93486082409682

Topological polar surface area  892.67

Aromaticity  0.0833333333333333

Average rotatable bonds  3.58333333333333

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  33

X logP energy  -0.890829999999915

Hydropathy 



Literature Information


Title  Signal Peptide Efficiency: From High-Throughput Data to Prediction and Explanation

DOI  10.1021/acssynbio.2c00328,

Publication Year  2023

PubMed ID  36649479,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.