General Information
SPKB ID SPKB06112
Signal sequence MRVKGIRKSYQQLWKGGTLLLGILMICSA
Length 29
Organism Human immunodeficiency virus type 1 (HIV-1)
UniProt ID NA,
Motif 1..29
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06112.cif
Physicochemical Information
Molecular weight 3265.04284
Aliphatic index 121.034482758621
Isoelectric point 11.1113421106711
Charge (pH=7) 4.93426744509256
Topological polar surface area 1262.87
Aromaticity 0.0689655172413793
Average rotatable bonds 3.93103448275862
Number of hydrogen bond donors 47
Number of hydrogen bond acceptors 44
X logP energy -8.53876000000003
Hydropathy 
Literature Information
Title Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations
DOI 10.1371/journal.ppat.1006812,
Publication Year 2018
PubMed ID 29370305,
Patent ID NA,
