General Information
SPKB ID SPKB06111
Signal sequence MRVKGIRKSYQRLWKGGTLLLGILMICSA
Length 29
Organism Human immunodeficiency virus type 1 (HIV-1)
UniProt ID NA,
Motif 1..29
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06111.cif
Physicochemical Information
Molecular weight 3293.09964
Aliphatic index 121.034482758621
Isoelectric point 11.6685690535232
Charge (pH=7) 5.93426413379231
Topological polar surface area 1281.68
Aromaticity 0.0689655172413793
Average rotatable bonds 3.96551724137931
Number of hydrogen bond donors 49
Number of hydrogen bond acceptors 44
X logP energy -8.54099000000004
Hydropathy 
Literature Information
Title Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations
DOI 10.1371/journal.ppat.1006812,
Publication Year 2018
PubMed ID 29370305,
Patent ID NA,
