General Information
SPKB ID SPKB06110
Signal sequence MRVKGIRKSYQYLWGGGTLLLGILMICSA
Length 29
Organism Human immunodeficiency virus type 1 (HIV-1)
UniProt ID NA,
Motif 1..29
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06110.cif
Physicochemical Information
Molecular weight 3228.96594
Aliphatic index 121.034482758621
Isoelectric point 10.453566304408
Charge (pH=7) 3.93371206472625
Topological polar surface area 1213.99
Aromaticity 0.103448275862069
Average rotatable bonds 3.75862068965517
Number of hydrogen bond donors 46
Number of hydrogen bond acceptors 43
X logP energy -7.35356
Hydropathy 
Literature Information
Title Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations
DOI 10.1371/journal.ppat.1006812,
Publication Year 2018
PubMed ID 29370305,
Patent ID NA,
