General Information
SPKB ID SPKB06107
Signal sequence MKVKGIRRNYQYLWRWGIMLLGICSA
Length 26
Organism Human immunodeficiency virus type 1 (HIV-1)
UniProt ID NA,
Motif 1..26
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06107.cif
Physicochemical Information
Molecular weight 3156.86454
Aliphatic index 105
Isoelectric point 10.9512605043128
Charge (pH=7) 4.933708753426
Topological polar surface area 1207.01
Aromaticity 0.153846153846154
Average rotatable bonds 4.03846153846154
Number of hydrogen bond donors 46
Number of hydrogen bond acceptors 40
X logP energy -5.67338999999996
Hydropathy 
Literature Information
Title Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations
DOI 10.1371/journal.ppat.1006812,
Publication Year 2018
PubMed ID 29370305,
Patent ID NA,
