General Information
SPKB ID SPKB06103
Signal sequence MKVKGIRRNYQHLWGWGIMLLGICSA
Length 26
Organism Human immunodeficiency virus type 1 (HIV-1)
UniProt ID NA,
Motif 1..26
Activity Information
Pathway SRP-dependent
Natural/Artificial Artificial
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB06103.cif
Physicochemical Information
Molecular weight 3031.69404
Aliphatic index 105
Isoelectric point 10.8884361488745
Charge (pH=7) 4.02547156985366
Topological polar surface area 1153.56
Aromaticity 0.115384615384615
Average rotatable bonds 3.88461538461538
Number of hydrogen bond donors 43
Number of hydrogen bond acceptors 39
X logP energy -6.28775999999995
Hydropathy 
Literature Information
Title Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations
DOI 10.1371/journal.ppat.1006812,
Publication Year 2018
PubMed ID 29370305,
Patent ID NA,
