SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB06100

Signal sequence   MRKSLITLGLASVIGTSSFLPFTSKTASA

Length  29

Organism  Bacillus subtilis

UniProt ID  NA,

Motif  1..29



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB06100.cif

Structure  SPKB06100.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2985.53224

Aliphatic index  101.0344828

Isoelectric point  11.82305527

Charge (pH=7)   2.99739092

Topological polar surface area  1185.57

Aromaticity  0.068965517

Average rotatable bonds  3.379310345

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  44

X logP energy  -14.02923

Hydropathy 



Literature Information


Title  Systematic Screening of Optimal Signal Peptides for Secretory Production of Heterologous Proteins in Bacillus subtilis

DOI  10.1021/acs.jafc.8b04183,

Publication Year  2018

PubMed ID  30463403,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.